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CRNXNASDAQ

Crinetics Pharmaceuticals Inc.

Crinetics Pharmaceuticals Inc.
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The next earnings date isn't available yet.

KPI highlights

FY25
Revenue $8M YoY +640.7%
Operating income $-517M margin -6714.8%
Net income $-465M YoY —
EPS $-4.95 YoY —
P/E —
ROE -46.9% Equity ratio 88% Typical equity ratios vary a lot by industry. Banks, brokerages, and other financial companies tend to run lower ratios because leverage (using other people's capital) is core to their business model — a low ratio there isn't a sign of financial weakness.

Company news

Ownership over time

Share of total shares outstanding (disclosed major holdings + undisclosed)（2018–2026）

機関投資家 15.2%未開示 84.8%201820192020202120222023202420252026
機関投資家 15.2%未開示 84.8%18Q319Q220Q120Q421Q322Q223Q123Q424Q325Q326Q1
機関投資家未開示・浮動株

「国内機関」は信託銀行の名義口座（年金・パッシブ・一部海外資本を含む）を集計し、実質保有者へは分解していません。分類は開示名称からの推定です。

Top shareholders — rank & share

Driehaus Capital M 6.7%Driehaus Capital Management LLCBAKER BROS. ADVISO 2.5%BAKER BROS. ADVISORS LPSiren, L.L.C. 2%Siren, L.L.C.First Light Asset 1.1%First Light Asset Management, LLCFisher Asset Manag 0.8%Fisher Asset Management, LLC201820192020202120222023202420252026
Driehaus Capital M 6.7%Driehaus Capital Management LLCBAKER BROS. ADVISO 2.5%BAKER BROS. ADVISORS LPSiren, L.L.C. 2%Siren, L.L.C.First Light Asset 1.1%First Light Asset Management, LLCFisher Asset Manag 0.8%Fisher Asset Management, LLC18Q319Q220Q120Q421Q322Q223Q123Q424Q325Q326Q1

Top shareholders — actual figures (as of 2026)

Holder Shares held Ratio Source
Driehaus Capital Management LLC 6,395,922 6.7% 13F
BAKER BROS. ADVISORS LP 2,351,465 2.5% 13F
Siren, L.L.C. 1,903,636 2.0% 13F
First Light Asset Management, LLC 1,089,670 1.1% 13F
Fisher Asset Management, LLC 762,702 0.8% 13F
Impax Asset Management Group plc 350,000 0.4% 13F
BRAUN STACEY ASSOCIATES INC 324,808 0.3% 13F
Foresite Capital Management VI LLC 212,010 0.2% 13F
SEGALL BRYANT & HAMILL, LLC 180,112 0.2% 13F
SILVERCREST ASSET MANAGEMENT GROUP LLC 163,633 0.2% 13F
NEW YORK STATE COMMON RETIREMENT FUND 141,618 0.1% 13F
RHUMBLINE ADVISERS 118,420 0.1% 13F
Russell Investments Group, Ltd. 107,297 0.1% 13F
AWM Investment Company, Inc. 100,000 0.1% 13F
Campbell & CO Investment Adviser LLC 83,617 0.1% 13F
MetLife Investment Management, LLC 54,326 0.1% 13F
BNP PARIBAS FINANCIAL MARKETS 45,269 0.0% 13F
GLENMEDE TRUST CO NA 29,245 0.0% 13F
その他機関投資家（13F 27社） 27,774 0.0% 13F
KLP KAPITALFORVALTNING AS 19,700 0.0% 13F
NATIXIS ADVISORS, LLC 18,458 0.0% 13F
DNB Asset Management AS 17,149 0.0% 13F
JONES FINANCIAL COMPANIES LLLP 16,283 0.0% 13F
Jump Financial, LLC 16,000 0.0% 13F
Jackson Creek Investment Advisors LLC 11,526 0.0% 13F
LOS ANGELES CAPITAL MANAGEMENT LLC 9,821 0.0% 13F

Source：SEC EDGAR（DEF 14A・13D/G・13F）　Classification inferred from disclosed names

F-Score (Piotroski)

2/9 1 of 9 items lack data

Checks financial health against 9 criteria and shows how many are met as a fraction (more ✓ marks is healthier). Items with no data are shown as “—” — they're simply excluded from judgment, not counted against the score.

✗ Positive ROA ROA -41.3%
✗ Positive operating cash flow $-378M
✗ ROA improved YoY -20.8% → -41.3%
✓ Operating CF exceeds net income (accrual quality) OCF $-378M / net income $-465M
✗ Equity ratio improved* Substitute for the original “decrease in long-term debt” 92.3% → 88.1%
✗ Current ratio improved 23.04× → 12.32×
✗ No dilution (shares outstanding did not increase) 92,926,000 → 95,575,000
— Gross margin improved No data
✓ Asset turnover improved 0.00× → 0.01×

This score is reference information based on our own financial metrics. It is NOT a credit rating issued by a credit rating agency under Article 66-27 of the Financial Instruments and Exchange Act, and is NOT investment advice or a recommendation. Make investment decisions at your own responsibility.

Fact checklist

FY25
Equity ratio 88.1%
Current ratio 12.3×
Years of positive operating CF 0 of last 10 yrs
Payout ratio —
Latest fiscal year result Loss (net loss $465M)

Performance history

Last 10 years
$0M$2M$4M$6M$8M FY16FY17FY18FY19FY20FY21FY22FY23FY24FY25

Income & assets

Unit: $1M
Item FY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
Revenue 0.592.052.431.190.071.084.744.011.047.70
Operating income -6.04-9.13-28.7-53.8-75.0-108-168-223-339-517
Ordinary income ——————————
Net income -6.02-9.16-27.1-50.4-73.8-108-164-215-298-465
Total assets —15.61711301833513526351,4351,126
Equity -6.20-15.01601171693323165391,325992

A “—” means data wasn't available for that period — it's not a display error or an unusual value.

Indicators & cash flow

Unit: $1M
Item FY16FY17FY18FY19FY20FY21FY22FY23FY24FY25
EPS ————$-2.42$-2.80$-3.15$-3.69$-3.69$-4.95
ROE 97.0%61.0%-16.9%-43.0%-43.7%-32.4%-51.8%-39.8%-22.5%-46.9%
Operating CF -5.47-9.48-19.5-46.4-62.0-88.6-115-169-230-378
Investing CF -0.19-0.30-11941.70.22-56.5-174-200-575174
Financing CF -0.0511.81700.071152531223911,01540.6
FCF ——————————

A “—” means data wasn't available for that period — it's not a display error or an unusual value.

Source: SEC EDGAR (10-K, etc.) (fetched 2026-07-03) *Some metrics supplemented from additional sources

Sector positioning

Relative standing within the sector
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Data provided by Twelve Data